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CDK7-IN-20 [CAS 3034210-97-1]
CDK7-IN-20 [CAS 3034210-97-1]
SKU:QM-0069687
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Product Details
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Description
CDK7-IN-20 is a potent, selective and irreversible CDK7 (CDK) inhibitor with an IC50 value of 4 nM. CDK7-IN-20 displays >206-fold selectivity for CDK7 over CDK1, CDK2, CDK3, CDK5, CDK6, CDK9 and CDK12 . CDK7-IN-20 has the potential for autosomal dominant polycystic kidney disease (ADPKD) research[1].
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CAS Number
[3034210-97-1]
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Molecular Formula
C30H26N6O3
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Molecular Weight
518.57
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Smiles
C=CC(NC1=CC=C(C=C1)C(NC2=NNC3=C2C=C(C=C3)C4=CC(NC[C@H](C5=CC=CC=C5)O)=CN=C4)=O)=O
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Target
CDK; GSK-3
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Isoform
CDK1; CDK12; CDK2; CDK3; CDK5; CDK6; CDK7; CDK9; GSK-3β
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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CDK7-IN-20 [CAS 3034210-97-1]
CDK7-IN-20 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.