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CDK8/19-IN-2 [CAS 3024381-54-9]

CDK8/19-IN-2 [CAS 3024381-54-9]

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SKU:QM-0082274

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  • Description

    CDK8/19-IN-2 (compound 12) is an orally active and potent cyclin-dependent kinase 8/19 (CDK8 and CDK19) inhibitor, with IC50 values of 2.08 and 2.49 nM, respectively. CDK8/19-IN-2 can be used for acute myeloid leukemia (AML), breast cancer, and lymphoma research[1].

  • CAS Number

    [3024381-54-9]

  • Molecular Formula

    C17H20Br2F2N4O

  • Molecular Weight

    494.17

  • Smiles

    BrC1=C(C=C2N(C(N3CCNCC3)=NC2=C1C(F)F)C4CCOCC4)Br

  • Target

    CDK; STAT

  • Isoform

    CDK19; CDK8

  • Shipping Conditions

    Room temperature

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CDK8/19-IN-2 [CAS 3024381-54-9]

CDK8/19-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.