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CDK8-IN-19

CDK8-IN-19

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SKU:QM-0013783

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  • Description

    CDK8-IN-19 (Compound 3d) is a CDK8 inhibitor with an IC50 of 25.08 nM. CDK8-IN-19 has a broad-spectrum anticancer activity, such as leukemia, melanoma and breast cancer, without significant cytotoxic effect on the normal Vero cells (mean IC50s of 2.87, 3.65, 3.79 and 45.48 μM, respectively) [1].

  • Molecular Formula

    C17H11Cl2N3OS2

  • Molecular Weight

    408.32

  • Smiles

    S=C(NC1=CC=C(Cl)C=C1Cl)NC(S/C2=C/C3=CC=CC=C3)=NC2=O

  • Target

    CDK; PI3K

  • Isoform

    CDK2; CDK8; PI3Kα

  • Shipping Conditions

    Room temperature

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CDK8-IN-19

CDK8-IN-19 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.