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CDK9-IN-27

CDK9-IN-27

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SKU:QM-0071610

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  • Description

    CDK9-IN-27 (Compound 6a) is a CDK9 inhibitor (IC50s: 0.424 μM) . CDK9-IN-27 induces apoptosis and cell cycle arrest at S stage. CDK9-IN-27 has cytotoxic action against HepG2, HCT-116 and MCF-7 cell lines, with IC50s of 10.31-40.34 μM. CDK9-IN-27 can be used for cancer research[1].

  • Molecular Formula

    C23H18ClN5O3

  • Molecular Weight

    447.87

  • Smiles

    ClC(C=C1)=CC=C1C(C(C(OCC)=O)=C(N)N2CC3=NC4=CC=CC=C4N3)=C(C#N)C2=O

  • Target

    CDK

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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CDK9-IN-27

CDK9-IN-27 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.