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CDK9-IN-33
CDK9-IN-33
SKU:QM-0098762
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Product Details
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Description
CDK9-IN-33 (compound C35) is a potent, selective and orally active CDK9 inhibitor with IC50 values of 17.44, 160, 316.30, 1771.00, >10000 nM for CDK9, CDK7, CDK2, CDK4, CDK6 respectively. CDK9-IN-33 induces apoptosis. CDK9-IN-33 decreases the protein expression of RPB1 CTD Ser2, RPB1, MCL1. CDK9-IN-33 shows anti-tumor activity[1].
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Molecular Formula
C23H31N7O2
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Molecular Weight
437.54
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Smiles
CC(C1=C2N=C(N=C(N2N=C1)NCC3=CC=C(C=C3)NC(CC)=O)NC4CCOCC4)C
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Target
Apoptosis; CDK
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Isoform
CDK2; CDK4; CDK6; CDK7; CDK9
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Shipping Conditions
Room temperature
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CDK9-IN-33
CDK9-IN-33 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.