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CDK9-IN-36
CDK9-IN-36
SKU:QM-0011184
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Product Details
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Description
CDK9-IN-36 (Compound T7) is a potent, selective and metabolically stable CDK9 inhibitor with an IC50 value of 1.2 nM. CDK9-IN-36 effectively suppresses cell proliferation, reduces colony formation, and induces apoptosis in Osimertinib -resistant NSCLC cells by downregulating Mcl-1. CDK9-IN-36 also demonstrates antitumor efficacy in a tumor xenograft model[1].
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Molecular Formula
C30H33F2N5O4
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Molecular Weight
565.61
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Smiles
FC1=C(C2=CC(OCCCCCCO3)=C(C=C2)F)N=C(NC4=CC=C(C(NC5CCN(C(C)=O)CC5)=O)C3=C4)N=C1
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Target
Apoptosis; CDK
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Isoform
CDK9
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Shipping Conditions
Room temperature
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CDK9-IN-36
CDK9-IN-36 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.