KI-CDK9d-32 [CAS 3054009-82-1]
KI-CDK9d-32 [CAS 3054009-82-1]
SKU:QM-0011599-01
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Product Details
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Description
KI-CDK9d-32 is a CDK9 PROTAC degrader (DC50: 0.89 nM). KI-CDK9d-32 promotes the ubiquitination and degradation of CDK9. KI-CDK9d-32 inhibits the MYC pathway and disrupts nucleolar homeostasis. KI-CDK9d-32 has anticancer activity. (Pink: CDK9 ligand ; Blue: E3 ligase CRBN ligand (HY-163233) ; Black: Linker (HY-W011657) ; E3 ligase CRBN ligand-linker conjugate (HY-173525) ).
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CAS Number
[3054009-82-1]
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Molecular Formula
C39H45N9O4
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Molecular Weight
703.83
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Smiles
O=C(N[C@H]1C[C@H](NC2=CC(CCC)=NC3=CC=NN23)CC1)C4=CC=C(CN5CCN(C6=CC7=C(C(N(C(CC8)C(NC8=O)=O)C7)=O)C=C6)CC5)C=C4
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Target
CDK; c-Myc; PROTACs
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Isoform
CDK9
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Purity
99.03
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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KI-CDK9d-32 [CAS 3054009-82-1]
KI-CDK9d-32 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.