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Minocycline-d6 (hydrochloride) [CAS 1035979-33-9]

Minocycline-d6 (hydrochloride) [CAS 1035979-33-9]

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SKU:QM-0073828

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  • Description

    Minocycline-d6 hydrochloride is deuterated labeled Minocycline hydrochloride. Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF) -1α inhibitor. Minocycline hydrochloride shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect[1][2][3][4][5][6][7].

  • CAS Number

    [1035979-33-9]

  • Molecular Formula

    C23H22D6ClN3O7

  • Molecular Weight

    499.97

  • Smiles

    O[C@]12[C@](C[C@@]3([H])C(C(C4=C(O)C=CC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=C4C3)=O)=C2O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C.Cl

  • Target

    Antibiotic; Apoptosis; Bacterial; Calcium Channel; HIF/HIF Prolyl-Hydroxylase; Isotope-Labeled Compounds; MDM-2/p53; Potassium Channel

  • Isoform

    Tetracycline

  • Solubility

    10 mM in DMSO

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

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Minocycline-d6 (hydrochloride) [CAS 1035979-33-9]

Minocycline-d6 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.