Minocycline-d6 (sulfate)
Minocycline-d6 (sulfate)
SKU:QM-0073829
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Product Details
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Description
Minocycline-d6 sulfate is deuterated labeled Minocycline. Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF) -1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect[1][2][3][4][5][6][7].
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Molecular Formula
C23H23D6N3O11S
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Molecular Weight
561.59
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Smiles
O[C@]12[C@](C[C@@]3([H])C(C(C4=C(O)C=CC(N(C([2H])([2H])[2H])C([2H])([2H])[2H])=C4C3)=O)=C2O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C)C.OS(O)(=O)=O
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Target
Antibiotic; Apoptosis; Bacterial; Calcium Channel; HIF/HIF Prolyl-Hydroxylase; Isotope-Labeled Compounds; MDM-2/p53; Potassium Channel
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Purity
95.21
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Minocycline-d6 (sulfate)
Minocycline-d6 (sulfate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.