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Mirdametinib [CAS 391210-10-9]

Mirdametinib [CAS 391210-10-9]

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SKU:QM-0081891-01

£94.75 GBP
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  • Description

    Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts[1][2][3].

  • CAS Number

    [391210-10-9]

  • Molecular Formula

    C16H14F3IN2O4

  • Molecular Weight

    482.19

  • Smiles

    O=C(C1=CC=C(C(F)=C1NC2=CC=C(I)C=C2F)F)NOC[C@H](O)CO

  • Target

    Apoptosis; Autophagy; MEK

  • Isoform

    MEK; MEK1; MEK2

  • Purity

    99.95

  • Solubility

    DMSO : ≥ 56 mg/mL

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H301, H373, H413

  • Precautions

    H301, H373, H413

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Variant Variant total Quantity Price Variant total
5 mgQM-0081891-01
5 mgQM-0081891-01
£94.75/ea
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10 mM - 1 mLQM-0081891-02
10 mM - 1 mLQM-0081891-02
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10 mgQM-0081891-03
10 mgQM-0081891-03
£186.08/ea
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25 mgQM-0081891-04
25 mgQM-0081891-04
£275.99/ea
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£275.99/ea £0.00
50 mgQM-0081891-05
50 mgQM-0081891-05
£336.74/ea
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£336.74/ea £0.00
100 mgQM-0081891-06
100 mgQM-0081891-06
£487.40/ea
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£487.40/ea £0.00

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Mirdametinib [CAS 391210-10-9]

Mirdametinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.