PI-103 [CAS 371935-74-9]

Size 5 mg 10 mM - 1 mL 10 mg 50 mg 100 mg

SKU:QM-0077718-01

£101.50 GBP

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Product Details

Description
PI-103 is a potent PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 also inhibits DNA-PK with an IC50 of 2 nM. PI-103 induces autophagy[1][2][3][4].
CAS Number
[371935-74-9]
Molecular Formula
C19H16N4O3
Molecular Weight
348.36
Smiles
OC1=CC(C2=NC3=C(C(N4CCOCC4)=N2)OC5=C3C=CC=N5)=CC=C1
Target
Apoptosis; Autophagy; DNA-PK; mTOR; PI3K
Isoform
MTORC1; mTORC2; PI3KC2α; PI3KC2β; PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ; Vps34
Purity
99.82
Solubility
DMSO : 10 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335
Precautions
H302, H315, H319, H335

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0077718-01	5 mgQM-0077718-01 £101.50/ea	£0.00	Quantity	£101.50/ea	£0.00

10 mM - 1 mLQM-0077718-02	10 mM - 1 mLQM-0077718-02 £109.38/ea	£0.00	Quantity	£109.38/ea	£0.00

10 mgQM-0077718-03	10 mgQM-0077718-03 £125.13/ea	£0.00	Quantity	£125.13/ea	£0.00

50 mgQM-0077718-04	50 mgQM-0077718-04 £381.69/ea	£0.00	Quantity	£381.69/ea	£0.00

100 mgQM-0077718-05	100 mgQM-0077718-05 £646.57/ea	£0.00	Quantity	£646.57/ea	£0.00

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PI-103 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.