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PLX-4720 [CAS 918505-84-7]
PLX-4720 [CAS 918505-84-7]
SKU:QM-0156538-01
£67.44 GBP
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Product Details
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Description
PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1 (Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.
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CAS Number
[918505-84-7]
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Molecular Formula
C17H14ClF2N3O3S
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Molecular Weight
413.83
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Smiles
O=S(NC1=CC=C(C(C(C2=CNC3=NC=C(C=C23)Cl)=O)=C1F)F)(CCC)=O
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Target
Raf
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Isoform
B-Raf
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Purity
99.9
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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PLX-4720 [CAS 918505-84-7]
PLX-4720 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.