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Rapamycin [CAS 53123-88-9]

Rapamycin [CAS 53123-88-9]

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QM-0081843-01

£59.16 GBP
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Product Details

  • Description

    Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1[1]. Rapamycin is an autophagy activator, an immunosuppressant[2].

  • CAS Number

    [53123-88-9]

  • Molecular Formula

    C51H79NO13

  • Molecular Weight

    914.17

  • Smiles

    O=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](O)CC4)OC)C)=O)=O

  • Target

    Antibiotic; Autophagy; Bacterial; Endogenous Metabolite; FKBP; Fungal; mTOR

  • Isoform

    FKBP12; Microbial Metabolite; mTORC1

  • Purity

    99.94

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0081843-01
5 mgQM-0081843-01
£59.16/ea		 £0.00
£59.16/ea £0.00
10 mgQM-0081843-02
10 mgQM-0081843-02
£78.82/ea		 £0.00
£78.82/ea £0.00
10 mM - 1 mLQM-0081843-03
10 mM - 1 mLQM-0081843-03
£88.00/ea		 £0.00
£88.00/ea £0.00
25 mgQM-0081843-04
25 mgQM-0081843-04
£89.13/ea		 £0.00
£89.13/ea £0.00
50 mgQM-0081843-05
50 mgQM-0081843-05
£94.75/ea		 £0.00
£94.75/ea £0.00
100 mgQM-0081843-06
100 mgQM-0081843-06
£116.13/ea		 £0.00
£116.13/ea £0.00
200 mgQM-0081843-07
200 mgQM-0081843-07
£215.24/ea		 £0.00
£215.24/ea £0.00
500 mgQM-0081843-08
500 mgQM-0081843-08
£365.90/ea		 £0.00
£365.90/ea £0.00
1 gQM-0081843-09
1 gQM-0081843-09
£622.26/ea		 £0.00
£622.26/ea £0.00
2 gQM-0081843-10
2 gQM-0081843-10
£1,013.50/ea		 £0.00
£1,013.50/ea £0.00
5 gQM-0081843-11
5 gQM-0081843-11
£1,857.92/ea		 £0.00
£1,857.92/ea £0.00
10 gQM-0081843-12
10 gQM-0081843-12
£2,786.18/ea		 £0.00
£2,786.18/ea £0.00
25 gQM-0081843-13
25 gQM-0081843-13
£5,196.74/ea		 £0.00
£5,196.74/ea £0.00
50 gQM-0081843-14
50 gQM-0081843-14
£7,768.90/ea		 £0.00
£7,768.90/ea £0.00
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Rapamycin [CAS 53123-88-9]

Rapamycin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.