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P-gp/CDK2-IN-1
P-gp/CDK2-IN-1
SKU:QM-0109425
Price on request
Quantity
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Product Details
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Description
P-gp/CDK2-IN-1 (Compound 4j) is an inhibitor for is inhibitor for P-glycoprotein (P-gp) and for cyclin-dependent kinase-2 (CDK2) . P-gp/CDK2-IN-1 inhibits the proliferation of cancer cells SW-480 and MCF-7 wit IC50 of 38.6 μM and 26.6 μM. P-gp/CDK2-IN-1 exhibits antioxidant efficacy with EC50 of 580 μM in DPPH experiment[1].
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Molecular Formula
C21H23NO8
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Molecular Weight
417.41
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Smiles
O=C(C1=C(N)OC(C=C(C)O2)=C(C2=O)C1C3=CC(OC)=C(OC)C(OC)=C3)OCC
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Target
CDK; P-glycoprotein
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Isoform
CDK2
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Shipping Conditions
Room temperature
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P-gp/CDK2-IN-1
P-gp/CDK2-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.