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PLK1-IN-12
PLK1-IN-12
SKU:QM-0010539
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Product Details
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Description
PLK1-IN-12 is a highly selective and orally active PLK1 inhibitor with an IC50 of 20 nM. PLK1-IN-12 shows more selective for PLK1 than PLK2 (IC50: >10000 nM) and PLK3 (IC50: 3953 nM) . PLK1-IN-12 exhibits anticancer potency across a broad spectrum of cell lines. PLK1-IN-12 can be used in anti-leukemia research[1].
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Molecular Formula
C28H40ClN7O3
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Molecular Weight
558.12
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Smiles
CN(C1=O)C(C=NC(NC2=C(C(Cl)=CC(N3CCN(CC3)C)=C2)OCCCO)=N4)=C4N([C@@H]1CC)C5CCCC5
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Target
Polo-like Kinase (PLK)
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Isoform
PLK1; PLK2; PLK3
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Shipping Conditions
Room temperature
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PLK1-IN-12
PLK1-IN-12 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.