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PLK1-IN-14
PLK1-IN-14
SKU:QM-0011331
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Quantity
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Product Details
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Description
PLK1-IN-14 (Compound Hit-4) is a selective PLK1 inhibitor. It has an IC50 of 22.61 pM against PLK1 and an IC50 of 0.09 nM for inhibiting the proliferation of DU - 145 prostate cancer cells. PLK1-IN-14 can be used in the research of prostate cancer[1].
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Molecular Formula
C41H55F5N8O3
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Molecular Weight
802.92
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Smiles
COC1=CC(C(NC2CCC(N3CCN(C[C@H]4CCC5(CCCC5)C4)CC3)CC2)=O)=C(F)C=C1NC6=NC=C(N(C)C(C(F)(F)CN7[C@H]8CCCC8(F)F)=O)C7=N6
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Target
Polo-like Kinase (PLK)
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Isoform
PLK1
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Shipping Conditions
Room temperature
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PLK1-IN-14
PLK1-IN-14 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.