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PLK4-IN-5
PLK4-IN-5
SKU:QM-0015750
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Quantity
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Product Details
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Description
PLK4-IN-5 is a PLK4 (IC50 = 0.8 nM) inhibitor. PLK4-IN-5 can inhibit MCF-7 cell clone formation, induce cell cycle arrest (S/G2 phase), and apoptosis. PLK4-IN-5 has anti proliferative activity against MCF-7 cells (IC50 = 0.48 μM) . PLK4-IN-5 can be used in the research of cancer such as breast cancer[1].
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Molecular Formula
C21H22ClN5O2S2
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Molecular Weight
476.01
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Smiles
NC1=CC=C(C=C1)SC2=NC(NC3=CC=C(C=C3)NC4CCS(=O)(CC4)=O)=NC=C2Cl
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Target
Apoptosis; Polo-like Kinase (PLK)
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Shipping Conditions
Room temperature
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PLK4-IN-5
PLK4-IN-5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.