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Topoisomerase IIα-IN-6
Topoisomerase IIα-IN-6
SKU:QM-0070074
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Product Details
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Description
Topoisomerase IIα-IN-6 (Compound 47d) is an inhibitor of DNA topoisomerase IIα/β. Topoisomerase IIα-IN-6 inhibits human topoisomerase IIα and human topoisomerase IIβ with IC50 values of 0.67 µM and 0.55 µM, respectively. Topoisomerase IIα-IN-6 has stable metabolism[1].
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Molecular Formula
C23H24Cl3N5O4
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Molecular Weight
540.83
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Smiles
CC1=C(C(Cl)=C(N1)C(NC2=CC=C(C=C2OCC3=CC=C(C=C3)C(NCCN)=O)C(N)=O)=O)Cl.Cl
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Target
Topoisomerase
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Isoform
Topo II
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Topoisomerase IIα-IN-6
Topoisomerase IIα-IN-6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.