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Topoisomerase IIα-IN-7
Topoisomerase IIα-IN-7
SKU:QM-0070080
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Product Details
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Description
Topoisomerase IIα-IN-7 is an DNA topoisomerase IIα inhibitor with an IC50 value of 7.7 µM. Topoisomerase IIα-IN-7 has broad-spectrum cytotoxicity to leukemia, lung, colon, melanoma, ovarian, kidney, prostate and breast cancer cells. Topoisomerase IIα-IN-7 has metabolic stability[1].
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Molecular Formula
C25H27Cl3N4O3
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Molecular Weight
537.87
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Smiles
O=C(NC1=C(OCC2=CC(C(NC3CCCNC3)=O)=CC=C2)C=CC=C1)C4=C(Cl)C(Cl)=C(C)N4.Cl
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Target
Topoisomerase
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Isoform
Topo II
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Topoisomerase IIα-IN-7
Topoisomerase IIα-IN-7 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.