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Tubulin degrader 1
Tubulin degrader 1
SKU:QM-0091691
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Product Details
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Description
Tubulin degrader 1 (Compound 5i) is a BML284 derivative that is an orally active colchicine-site noncovalent tubulin degradation agent with IC50 values ranging from 0.02 to 0.05 μM against the five tumor cell lines (Hela, HCT116, MCF-7, K562 and Molm-13). Tubulin degrader 1 has antiproliferative activity that effectively suppressed tumor growth[1].
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Molecular Formula
C20H19N5O
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Molecular Weight
345.4
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Smiles
COC1=CC=CC(C2=CC(NCC3=CC4=C(NC=C4)C=C3)=NC(N)=N2)=C1
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Target
Microtubule/Tubulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Tubulin degrader 1
Tubulin degrader 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.