Tubulin/MMP-IN-3
Tubulin/MMP-IN-3
SKU:QM-0010211
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Product Details
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Description
Tubulin/MMP-IN-3 (Compound 15j) is the dual inhibitor for tubulin polymerization and MMP, and inhibits MMP-2 and MMP-9 with IC50 of 21.13 μM and 19.24 μM. Tubulin/MMP-IN-3 inhibits NF-κB signaling pathway, causes mitochondrial dysfunction and the apoptosis through a mitochondrial-dependent pathway. Tubulin/MMP-IN-3 exhibits antiproliferative activity in a variety of cancer cells, arrests the cell cycle at G2/M phase, and exhibits antitumor efficacy in mouse models[1].
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Molecular Formula
C38H41N2O12P
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Molecular Weight
748.71
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Smiles
CCOP(OCC)(C(NC1=CC=C(CC(OC2=C(OC)C=CC(/C=C/C(C3=CC(OC)=C(OC)C(OC)=C3)=O)=C2)=O)C=C1)C4=CC([N+]([O-])=O)=CC=C4)=O
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Target
Apoptosis; Microtubule/Tubulin; MMP; NF-κB
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Shipping Conditions
Room temperature
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Tubulin/MMP-IN-3
Tubulin/MMP-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.