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Tubulin polymerization-IN-16 [CAS 2296731-38-7]
Tubulin polymerization-IN-16 [CAS 2296731-38-7]
SKU:QM-0066772
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Product Details
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Description
Tubulin polymerization-IN-16 (compound 5g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-16 shows most potent against cancer cells, with IC50 values of 0.084-0.221 μM. Tubulin polymerization-IN-16 potently disrupts microtubule/tubulin dynamics, induces cell cycle arrest at G2/M phase in SGC-7901 cells[1].
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CAS Number
[2296731-38-7]
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Molecular Formula
C24H27N5O5
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Molecular Weight
465.5
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Smiles
COC1=CC(C(C2=NN(N=C2N3CCN(CC3)C(C)=O)C4=CC=CC=C4)=O)=CC(OC)=C1OC
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Target
Microtubule/Tubulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Tubulin polymerization-IN-16 [CAS 2296731-38-7]
Tubulin polymerization-IN-16 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.