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Tubulin polymerization-IN-46
Tubulin polymerization-IN-46
SKU:QM-0072072
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Quantity
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Product Details
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Description
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/Tubulin inhibitor that inhibits tubulin polymerization and induces apoptosis. Tubulin polymerization-IN-46 inhibits mitosis and arrests MCF-7 cells in the G2/M phase. Tubulin polymerization-IN-46 has anti-proliferative activity against MCF-7 breast cancer cells with an IC50 of 10 nM[1].
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Molecular Formula
C22H25NO6
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Molecular Weight
399.44
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Smiles
O=C1N(C2=CC(OC)=C(OC)C(OC)=C2)[C@@H](C3=CC=C(OC)C(O)=C3)[C@@H]1C(C)=C
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Target
Microtubule/Tubulin; Mitosis
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Tubulin polymerization-IN-46
Tubulin polymerization-IN-46 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.