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Tubulin polymerization-IN-49
Tubulin polymerization-IN-49
SKU:QM-0072554
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Product Details
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Description
Tubulin polymerization-IN-49 (compound 12d) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-49 bound to colchicine site on tubulin and inhibited tubulin polymerization. Tubulin polymerization-IN-49 induces cell cycle arrest at G2/M phase and apoptosis. Tubulin polymerization-IN-49 has anticancer active and prevents tumor generation, inhibits tumor proliferation and angiogenesis[1].
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Molecular Formula
C20H24O5
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Molecular Weight
344.4
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Smiles
OC1=C(OC)C=CC(CC2CC3=CC(OC)=C(OC)C(OC)=C3C2)=C1
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Target
Microtubule/Tubulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Tubulin polymerization-IN-49
Tubulin polymerization-IN-49 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.