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Tubulin polymerization-IN-64
Tubulin polymerization-IN-64
SKU:QM-0133405
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Product Details
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Description
Tubulin polymerization-IN-64 (Compound 8a) is an inhibitor for tubulin polymerization by occupying the colchicine binding site of tubulin, with IC50 of 6.9 μM. Tubulin polymerization-IN-64 inhibits proliferations of cancer cells A549, HeLa, HCT116 and HT-29, with IC50s of 2.42, 10.33, 6.28, 5.33 μM, respectively. Tubulin polymerization-IN-64 arrests cell cycle at G2/M phase, induces apoptosis in A549[1].
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Molecular Formula
C25H25NO6
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Molecular Weight
435.47
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Smiles
O=C(/C(C1=CC(OC)=C(C(OC)=C1)OC)=C/C2=CC=C(C(O)=C2)OC)NC3=CC=CC=C3
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Target
Apoptosis; Microtubule/Tubulin
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Shipping Conditions
Room temperature
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Tubulin polymerization-IN-64
Tubulin polymerization-IN-64 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.