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Tubulin polymerization-IN-66
Tubulin polymerization-IN-66
SKU:QM-0120174
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Product Details
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Description
Tubulin polymerization-IN-66 (Compound 13) inhibits colony formation and tubulin polymerization. Tubulin polymerization-IN-66 induces apoptosis. Tubulin polymerization-IN-66 inhibits cell viability of A549, A2780, SKOV3, HCC827 cells, with IC50s of 0.84, 0.38, 0.31, 0.34 nM respectively. Tubulin polymerization-IN-66 is also active against the Paclitaxel -resistant cancer cell line A2780/T and its parental cell line A2780[1].
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Molecular Formula
C15H11ClN4O2S
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Molecular Weight
346.79
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Smiles
ClC1=NC2=C(SC=C2)C(N3C4=CC=C(OC)C=C4NC(C3)=O)=N1
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Target
Apoptosis; Microtubule/Tubulin
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Shipping Conditions
Room temperature
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Tubulin polymerization-IN-66
Tubulin polymerization-IN-66 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.