Tubulin polymerization-IN-68 [CAS 2924156-96-5]
Tubulin polymerization-IN-68 [CAS 2924156-96-5]
SKU:QM-0133975
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Product Details
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Description
Tubulin polymerization-IN-68 (compound 32) is a tubulin inhibitor that can inhibit tubulin polymerization and destroy the cellular microtubule network. Tubulin polymerization-IN-68 can upregulate the expression of PARP-1 and caspase-3 and induce cell apoptosis, and has anticancer activity. Tubulin polymerization-IN-68 can effectively inhibit HepG2 (IC50=93 nM) and significantly inhibit the growth of HepG2 xenograft tumors in nude mice by oral administration[1].
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CAS Number
[2924156-96-5]
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Molecular Formula
C16H13N3O
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Molecular Weight
263.29
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Smiles
O=C1NC(C2=CC3=C(NC=C3)C=C2)NC4=C1C=CC=C4
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Target
Apoptosis; Caspase; Microtubule/Tubulin; PARP
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Shipping Conditions
Room temperature
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Tubulin polymerization-IN-68 [CAS 2924156-96-5]
Tubulin polymerization-IN-68 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.