1 1

UV Cleavable Biotin-PEG2-Azide [CAS 1192802-98-4]

UV Cleavable Biotin-PEG2-Azide [CAS 1192802-98-4]

Size

QM-0147293-01

£464.31 GBP
Sale Sold out
Shipping calculated at checkout.
Shipping calculated at checkout.
View full details

Product Details

  • Description

    UV Cleavable Biotin-PEG2-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. UV Cleavable Biotin-PEG2-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

  • CAS Number

    [1192802-98-4]

  • Molecular Formula

    C38H51N7O9S

  • Molecular Weight

    781.92

  • Smiles

    O=C(OC(C1=CC=CC(OCC(NCCOCCOCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O)=O)=C1)C(C4=CC=CC=C4)=O)CCCCCN=[N+]=[N-]

  • Target

    PROTAC Linkers

  • Isoform

    PEG Linkers

  • Purity

    95.58

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302-H315-H319-H335

  • Precautions

    P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
Learn more
Variant Variant total Quantity Price Variant total
10 mgQM-0147293-01
10 mgQM-0147293-01
£464.31/ea		 £0.00
£464.31/ea £0.00
25 mgQM-0147293-02
25 mgQM-0147293-02
£565.16/ea		 £0.00
£565.16/ea £0.00
100 mgQM-0147293-03
100 mgQM-0147293-03
£1,380.42/ea		 £0.00
£1,380.42/ea £0.00
View cart
0

Total items

£0.00

Product subtotal

Taxes, discounts and shipping calculated at checkout.
View cart

Related Products

Other industry favorites

UV Cleavable Biotin-PEG2-Azide [CAS 1192802-98-4]

UV Cleavable Biotin-PEG2-Azide (CAS 1192802-98-4) is a certified click chemistry reagent supplied by Quantimol for laboratory and scientific research.

This compound is a photocleavable biotin-PEG-azide bifunctional reagent featuring a UV-cleavable nitrobenzyl linker, a PEG2 spacer, and a terminal azide group. It is widely used as a PROTAC linker and in bioorthogonal chemistry workflows. The azide group enables copper-catalysed azide-alkyne cycloaddition (CuAAC) with alkyne-bearing molecules, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN groups. UV irradiation cleaves the nitrobenzyl linker, releasing the biotinylated cargo for downstream streptavidin-based capture or detection.

Key properties:

  • Reactive group: Azide (click chemistry)
  • Cleavage: UV-cleavable nitrobenzyl linker (365 nm)
  • Affinity tag: Biotin (streptavidin-compatible)
  • Spacer: PEG2
  • CAS Number: 1192802-98-4
  • Purity: ≥95% (HPLC)
  • Storage: -20°C, protected from light
  • Solubility: DMSO (recommended)

Applications: PROTAC linker synthesis, CuAAC and SPAAC click chemistry, photoaffinity labelling, streptavidin pull-down assays, chemical proteomics, bioorthogonal bioconjugation.

Supplied by Quantimol as a certified reference standard for research use only. Not for human or veterinary use.