VMD-928 [CAS 1802770-18-8]
VMD-928 [CAS 1802770-18-8]
SKU:QM-0009947-01
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Product Details
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Description
VMD-928 is an orally active, allosteric, irreversible and selective tropomyosin receptor kinase A (TrkA) inhibitor. VMD-928 blocks the downstream signaling pathways triggered by the binding of nerve growth factor (NGF) to TrkA, thereby inhibiting cell proliferation, invasion, and promoting cancer cell death. VMD-928 is promising for research of various cancers, including prostate cancer, thymic carcinoma, mesothelioma, squamous cell carcinoma of the head and neck, squamous cell carcinoma of the lung, ovarian cancer, hepatocellular carcinoma[1][2].
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CAS Number
[1802770-18-8]
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Molecular Formula
C31H32N4O4
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Molecular Weight
524.61
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Smiles
O=C(C1=CC=C(NC(C=C(N2CCN(C3CCCCC3)CC2)C(N)=C4C(C5=C6C=CC=C5)=O)=C4C6=O)C=C1)O
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Target
Trk Receptor
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Shipping Conditions
Room temperature
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VMD-928 [CAS 1802770-18-8]
VMD-928 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.