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Olaparib [CAS 763113-22-0]
Olaparib [CAS 763113-22-0]
SKU:QM-0077969-01
£65.37 GBP
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Product Details
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Description
Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[1][2][3][4].
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CAS Number
[763113-22-0]
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Molecular Formula
C24H23FN4O3
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Molecular Weight
434.46
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Smiles
O=C(C1=CC(CC(C2=C3C=CC=C2)=NNC3=O)=CC=C1F)N4CCN(C(C5CC5)=O)CC4
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Target
Autophagy; Mitophagy; PARP
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Isoform
PARP1; PARP2; TNKS1/PARP5A
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Purity
99.98
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Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Olaparib [CAS 763113-22-0]
Olaparib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.