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Rucaparib [CAS 283173-50-2]

Rucaparib [CAS 283173-50-2]

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SKU:QM-0112089-01

£122.88 GBP
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  • Description

    Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research[1][2][3][4].

  • CAS Number

    [283173-50-2]

  • Molecular Formula

    C19H18FN3O

  • Molecular Weight

    323.36

  • Smiles

    FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1

  • Target

    PARP

  • Isoform

    PARP1; PARP2; PARP3

  • Concentration

    10mM

  • Purity

    99.97

  • Solubility

    DMSO : 70 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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5 mgQM-0112089-01
5 mgQM-0112089-01
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10 mM - 1 mLQM-0112089-02
10 mM - 1 mLQM-0112089-02
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10 mgQM-0112089-03
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50 mgQM-0112089-04
50 mgQM-0112089-04
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100 mgQM-0112089-05
100 mgQM-0112089-05
£636.85/ea
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Rucaparib [CAS 283173-50-2]

Rucaparib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.