1
/
of
1
SP600125 [CAS 129-56-6]
SP600125 [CAS 129-56-6]
SKU:QM-0139909-01
£59.16 GBP
Shipping calculated at checkout.
Shipping calculated at checkout.
Quantity
Couldn't load pickup availability
![SP600125 [CAS 129-56-6]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
SP600125 is an orally active, reversible, and ATP-competitive JNK inhibitor with IC50s of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. SP600125 is a potent ferroptosis inhibitor. SP600125 induces the transformation of bladder cancer cells from autophagy to apoptosis[1][2][3].
-
CAS Number
[129-56-6]
-
Molecular Formula
C14H8N2O
-
Molecular Weight
220.23
-
Smiles
O=C1C2=C3C(NN=C3C4=C1C=CC=C4)=CC=C2
-
Target
Apoptosis; Autophagy; Ferroptosis; JNK
-
Isoform
JNK1; JNK2; JNK3
-
Concentration
10mM
-
Purity
99.73
-
Solubility
DMSO : 11.67 mg/mL (ultrasonic; warming; heat to 60°C)
-
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
-
Shipping Conditions
Room Temperature
-
Hazard Statement
H302, H315, H319, H335
-
Precautions
H302, H315, H319, H335
Related Products
- QM-0083620-01 SB-431542 (GMP) [CAS 301836-41-9]
- QM-0083621-01 SB-431542 (Standard) [CAS 301836-41-9]
- QM-0083619-01 SB-431542 [CAS 301836-41-9]
- QM-0153897-01 Sonidegib (diphosphate) [CAS 1218778-77-8]
- QM-0008259-01 Sonidegib (Standard) [CAS 956697-53-3]
- QM-0153899-01 Sonidegib [CAS 956697-53-3]
- QM-0017434-01 Selumetinib (Standard) [CAS 606143-52-6]
- QM-0156439-01 Selumetinib [CAS 606143-52-6]
- QM-0002558-01 Adezmapimod (Standard) [CAS 152121-47-6]
- QM-0081898-01 Adezmapimod [CAS 152121-47-6]
Other industry favorites
- QM-0083620-01 SB-431542 (GMP) [CAS 301836-41-9]
- QM-0083621-01 SB-431542 (Standard) [CAS 301836-41-9]
- QM-0112089-01 Rucaparib [CAS 283173-50-2]
- QM-0081845-01 Rapamycin (GMP Like) [CAS 53123-88-9]
- QM-0081750-01 Sorafenib (Standard) [CAS 284461-73-0]
- QM-0081737-01 Sorafenib [CAS 284461-73-0]
SP600125 [CAS 129-56-6]
SP600125 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.