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Ruxolitinib (phosphate) [CAS 1092939-17-7]
Ruxolitinib (phosphate) [CAS 1092939-17-7]
SKU:QM-0156479-01
£94.75 GBP
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Product Details
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Description
Ruxolitinib phosphate (INCB018424 phosphate) is a potent JAK1/2 inhibitor with IC50s of 3.3 nM/2.8 nM, respectively, showing more than 130-fold selectivity over JAK3.
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CAS Number
[1092939-17-7]
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Molecular Formula
C17H21N6O4P
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Molecular Weight
404.36
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Smiles
N#CC[C@H](C1CCCC1)N2N=CC(C3=C4C=CNC4=NC=N3)=C2.O=P(O)(O)O
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Target
Autophagy; JAK; Mitophagy
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Isoform
JAK1; JAK2; JAK3; Tyk2
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Purity
99.97
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Solubility
DMSO : 220 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Ruxolitinib (phosphate) [CAS 1092939-17-7]
Ruxolitinib (phosphate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.