SB 202190 [CAS 152121-30-7]
SB 202190 [CAS 152121-30-7]
SKU:QM-0081949-01
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Product Details
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Description
SB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits[1][2]. SB202190 induces autophagy[3].
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CAS Number
[152121-30-7]
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Molecular Formula
C20H14FN3O
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Molecular Weight
331.34
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Smiles
FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C(O)C=C4)=N2)C=C1
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Target
Apoptosis; Autophagy; Organoid; p38 MAPK
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Isoform
P38α; p38β
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Purity
99.89
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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SB 202190 [CAS 152121-30-7]
SB 202190 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.