Rucaparib (phosphate) [CAS 459868-92-9]
Rucaparib (phosphate) [CAS 459868-92-9]
SKU:QM-0112085-01
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Product Details
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Description
Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research[1][2][3][4].
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CAS Number
[459868-92-9]
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Molecular Formula
C19H21FN3O5P
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Molecular Weight
421.36
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Smiles
O=P(O)(O)O.FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1
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Target
PARP
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Isoform
PARP1; PARP2; PARP3
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Purity
99.76
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Solubility
DMSO : ≥ 33 mg/mL|H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Rucaparib (phosphate) [CAS 459868-92-9]
Rucaparib (phosphate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.