SB-431542 [CAS 301836-41-9]

Size 5 mg 10 mg 10 mM - 1 mL 50 mg 100 mg

SKU:QM-0083619-01

£95.88 GBP

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Product Details

Description
SB-431542 is a TGF-β receptor kinase inhibitor (TRKI) . SB-431542 has inhibitory activity for ALK4, ALK5 and ALK7 with IC50 values of 1 μM, 0.75 μM and 2 μM, respectively. SB-431542 also inhibits TGF-β-induced transcription, gene expression, apoptosis, and growth suppression. SB-431542 can be used for the research of cancer and signal transduction pathways[1][2][3].
CAS Number
[301836-41-9]
Molecular Formula
C22H16N4O3
Molecular Weight
384.39
Smiles
O=C(C1=CC=C(C=C1)C2=NC(C3=CC=C4OCOC4=C3)=C(N2)C5=NC=CC=C5)N
Target
Apoptosis; Organoid; TGF-β Receptor
Isoform
ALK4; ALK5; ALK7
Purity
99.85
Solubility
DMSO : 50 mg/mL (ultrasonic) |Ethanol : 11.17 mg/mL (ultrasonic; warming)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335
Precautions
H302, H315, H319, H335

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0083619-01	5 mgQM-0083619-01 £95.88/ea	£0.00	Quantity	£95.88/ea	£0.00

10 mgQM-0083619-02	10 mgQM-0083619-02 £136.38/ea	£0.00	Quantity	£136.38/ea	£0.00

10 mM - 1 mLQM-0083619-03	10 mM - 1 mLQM-0083619-03 £148.75/ea	£0.00	Quantity	£148.75/ea	£0.00

50 mgQM-0083619-04	50 mgQM-0083619-04 £501.98/ea	£0.00	Quantity	£501.98/ea	£0.00

100 mgQM-0083619-05	100 mgQM-0083619-05 £893.21/ea	£0.00	Quantity	£893.21/ea	£0.00

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SB-431542 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.