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Selumetinib [CAS 606143-52-6]
Selumetinib [CAS 606143-52-6]
SKU:QM-0156439-01
£117.25 GBP
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Product Details
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Description
Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation.
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CAS Number
[606143-52-6]
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Molecular Formula
C17H15BrClFN4O3
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Molecular Weight
457.68
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Smiles
O=C(C1=C(C(F)=C2N=CN(C2=C1)C)NC3=CC=C(C=C3Cl)Br)NOCCO
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Target
Apoptosis; MEK
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Isoform
MEK; MEK1; MEK2
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Purity
99.87
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Solubility
DMSO : 20.83 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Selumetinib [CAS 606143-52-6]
Selumetinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.