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SR17018 [CAS 2134602-45-0]

SR17018 [CAS 2134602-45-0]

Size

QM-0137074-01

£103.75 GBP
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Product Details

  • Description

    SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.

  • CAS Number

    [2134602-45-0]

  • Molecular Formula

    C19H18Cl3N3O

  • Molecular Weight

    410.72

  • Smiles

    O=C1NC2=CC(Cl)=C(Cl)C=C2N1C3CCN(CC4=CC=C(Cl)C=C4)CC3

  • Target

    Opioid Receptor

  • Isoform

    μ Opioid Receptor/MOR

  • Purity

    98.01

  • Solubility

    DMSO : 12.5 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H315, H317, H318, H334, H335, H341, H361, H370, H413

  • Precautions

    H315, H317, H318, H334, H335, H341, H361, H370, H413
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Variant Variant total Quantity Price Variant total
5 mgQM-0137074-01
5 mgQM-0137074-01
£103.75/ea		 £0.00
£103.75/ea £0.00
10 mM - 1 mLQM-0137074-02
10 mM - 1 mLQM-0137074-02
£111.63/ea		 £0.00
£111.63/ea £0.00
10 mgQM-0137074-03
10 mgQM-0137074-03
£188.51/ea		 £0.00
£188.51/ea £0.00
25 mgQM-0137074-04
25 mgQM-0137074-04
£351.32/ea		 £0.00
£351.32/ea £0.00
50 mgQM-0137074-05
50 mgQM-0137074-05
£539.64/ea		 £0.00
£539.64/ea £0.00
100 mgQM-0137074-06
100 mgQM-0137074-06
£828.82/ea		 £0.00
£828.82/ea £0.00
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SR17018 [CAS 2134602-45-0]

SR17018 (CAS 2134602-45-0) is a certified reference standard supplied by Quantimol for laboratory and scientific research.

SR17018 is a G protein-biased mu-opioid receptor (MOR) agonist with an EC50 of 97 nM (GTPγS binding assay). Biased MOR agonists preferentially activate G protein signalling over β-arrestin recruitment, a mechanism associated with reduced opioid side effects such as respiratory depression and tolerance. SR17018 is a key tool compound in the study of opioid receptor pharmacology and the development of safer analgesics.

Key properties:

  • Target: Mu-opioid receptor (MOR / OPRM1)
  • Mechanism: G protein-biased MOR agonist
  • CAS Number: 2134602-45-0
  • EC50: 97 nM (GTPγS binding)
  • Purity: ≥98% (HPLC)
  • Storage: -20°C, protected from light
  • Solubility: DMSO (recommended)

Applications: Opioid receptor pharmacology, biased agonism research, pain biology, analgesic drug discovery, β-arrestin vs G protein signalling studies.

Supplied by Quantimol as a certified reference standard for research use only. Not for human or veterinary use.