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Regorafenib [CAS 755037-03-7]

Regorafenib [CAS 755037-03-7]

Size

QM-0083191-01

£65.37 GBP
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Product Details

  • Description

    Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity[1].

  • CAS Number

    [755037-03-7]

  • Molecular Formula

    C21H15ClF4N4O3

  • Molecular Weight

    482.82

  • Smiles

    O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(OC3=CC(C(NC)=O)=NC=C3)C=C2F

  • Target

    Autophagy; c-Kit; FGFR; PDGFR; Raf; RET; Tie; VEGFR

  • Isoform

    B-Raf; C-Raf; PDGFRβ; Tie2; VEGFR1/Flt-1; VEGFR2/KDR/Flk-1; VEGFR3/Flt-4

  • Purity

    99.93

  • Solubility

    DMSO : 125 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0083191-01
5 mgQM-0083191-01
£65.37/ea		 £0.00
£65.37/ea £0.00
10 mgQM-0083191-02
10 mgQM-0083191-02
£94.75/ea		 £0.00
£94.75/ea £0.00
10 mM - 1 mLQM-0083191-03
10 mM - 1 mLQM-0083191-03
£101.50/ea		 £0.00
£101.50/ea £0.00
50 mgQM-0083191-04
50 mgQM-0083191-04
£200.66/ea		 £0.00
£200.66/ea £0.00
100 mgQM-0083191-05
100 mgQM-0083191-05
£275.99/ea		 £0.00
£275.99/ea £0.00
500 mgQM-0083191-06
500 mgQM-0083191-06
£539.64/ea		 £0.00
£539.64/ea £0.00
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Regorafenib [CAS 755037-03-7]

Regorafenib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.