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Sunitinib (Malate) [CAS 341031-54-7]

Sunitinib (Malate) [CAS 341031-54-7]

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QM-0081893-01

£94.75 GBP
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Product Details

  • Description

    Sunitinib (SU 11248) Malat is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib Malat, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation[2].

  • CAS Number

    [341031-54-7]

  • Molecular Formula

    C26H33FN4O7

  • Molecular Weight

    532.56

  • Smiles

    O=C(NCCN(CC)CC)C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)F)=O)=C1C)C.O=C([C@H](CC(O)=O)O)O

  • Target

    Apoptosis; Autophagy; IRE1; Mitophagy; PDGFR; VEGFR

  • Isoform

    PDGFRβ; VEGFR2/KDR/Flk-1

  • Concentration

    10mM

  • Purity

    99.61

  • Solubility

    DMSO : ≥ 15 mg/mL|H2O : 12.5 mg/mL (ultrasonic; adjust pH to 3 with HCl) |H2O : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H360, H372

  • Precautions

    H360, H372
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Variant Variant total Quantity Price Variant total
100 mgQM-0081893-01
100 mgQM-0081893-01
£94.75/ea		 £0.00
£94.75/ea £0.00
10 mM - 1 mLQM-0081893-02
10 mM - 1 mLQM-0081893-02
£101.50/ea		 £0.00
£101.50/ea £0.00
200 mgQM-0081893-03
200 mgQM-0081893-03
£136.38/ea		 £0.00
£136.38/ea £0.00
500 mgQM-0081893-04
500 mgQM-0081893-04
£193.37/ea		 £0.00
£193.37/ea £0.00
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Sunitinib (Malate) [CAS 341031-54-7]

Sunitinib (Malate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.