A-769662 [CAS 844499-71-4]
A-769662 [CAS 844499-71-4]
SKU:QM-0156411-01
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Product Details
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Description
A-769662 is a AMP-activated protein kinase (AMPK) activator. A-769662 inhibits the function of the 26S proteasome by an AMPK-independent mechanism and leads to cell cycle arrest. A-769662 directly stimulates partially purified rat liver AMPK (EC50 = 0.8 μM) and inhibits fatty acid synthesis in primary rat hepatocytes (IC50 = 3.2 μM) . A-769662 can alleviate the symptoms of metabolic diseases such as type 2 diabetes[1][2][3][4].
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CAS Number
[844499-71-4]
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Molecular Formula
C20H12N2O3S
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Molecular Weight
360.39
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Smiles
N#CC1C(C2=C(NC1=O)SC=C2C3=CC=C(C4=CC=CC=C4O)C=C3)=O
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Target
AMPK
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Isoform
AMPK
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Purity
99.33
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Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 80°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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A-769662 [CAS 844499-71-4]
A-769662 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.