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Bexarotene [CAS 153559-49-0]
Bexarotene [CAS 153559-49-0]
SKU:QM-0147591-01
£117.25 GBP
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Product Details
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Description
Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC50s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC50 >10000 nM) [1][2][3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma.
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CAS Number
[153559-49-0]
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Molecular Formula
C24H28O2
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Molecular Weight
348.48
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Smiles
CC1(C2=C(C(C)(CC1)C)C=C(C(C(C3=CC=C(C=C3)C(O)=O)=C)=C2)C)C
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Target
Autophagy; RAR/RXR
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Purity
99.9
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Solubility
DMSO : 60 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Bexarotene [CAS 153559-49-0]
Bexarotene is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.