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Cabozantinib (S-malate) [CAS 1140909-48-3]

Cabozantinib (S-malate) [CAS 1140909-48-3]

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SKU:QM-0139918-01

£78.82 GBP
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  • Description

    Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.

  • CAS Number

    [1140909-48-3]

  • Molecular Formula

    C32H30FN3O10

  • Molecular Weight

    635.59

  • Smiles

    O=C([C@H](CC(O)=O)O)O.O=C(NC1=CC=C(C=C1)OC2=CC=NC3=CC(OC)=C(C=C23)OC)C4(CC4)C(NC5=CC=C(C=C5)F)=O

  • Target

    Apoptosis; VEGFR

  • Isoform

    VEGFR2/KDR/Flk-1

  • Purity

    99.9

  • Solubility

    DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0139918-01
5 mgQM-0139918-01
£78.82/ea
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£78.82/ea £0.00
10 mgQM-0139918-02
10 mgQM-0139918-02
£106.00/ea
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£106.00/ea £0.00
50 mgQM-0139918-03
50 mgQM-0139918-03
£129.63/ea
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£129.63/ea £0.00
100 mgQM-0139918-04
100 mgQM-0139918-04
£200.66/ea
£0.00
£200.66/ea £0.00
200 mgQM-0139918-05
200 mgQM-0139918-05
£288.14/ea
£0.00
£288.14/ea £0.00
500 mgQM-0139918-06
500 mgQM-0139918-06
£527.50/ea
£0.00
£527.50/ea £0.00

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Cabozantinib (S-malate) [CAS 1140909-48-3]

Cabozantinib (S-malate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.