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Cabozantinib (S-malate) [CAS 1140909-48-3]
Cabozantinib (S-malate) [CAS 1140909-48-3]
SKU:QM-0139918-01
£78.82 GBP
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Product Details
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Description
Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
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CAS Number
[1140909-48-3]
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Molecular Formula
C32H30FN3O10
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Molecular Weight
635.59
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Smiles
O=C([C@H](CC(O)=O)O)O.O=C(NC1=CC=C(C=C1)OC2=CC=NC3=CC(OC)=C(C=C23)OC)C4(CC4)C(NC5=CC=C(C=C5)F)=O
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Target
Apoptosis; VEGFR
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Isoform
VEGFR2/KDR/Flk-1
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Purity
99.9
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Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Cabozantinib (S-malate) [CAS 1140909-48-3]
Cabozantinib (S-malate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.