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Cobimetinib [CAS 934660-93-2]
Cobimetinib [CAS 934660-93-2]
SKU:QM-0143346-01
£136.38 GBP
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Product Details
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Description
Cobimetinib (GDC-0973, RG7420) is a potent, selective and oral MEK1 inhibitor with an IC50 of 4.2 nM for MEK1.
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CAS Number
[934660-93-2]
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Molecular Formula
C21H21F3IN3O2
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Molecular Weight
531.31
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Smiles
OC1([C@H]2NCCCC2)CN(C1)C(C3=C(C(F)=C(C=C3)F)NC4=C(C=C(C=C4)I)F)=O
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Target
Apoptosis; MEK
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Isoform
MEK1
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Purity
99.81
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Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Cobimetinib [CAS 934660-93-2]
Cobimetinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.