Skip to product information
1 of 1

Crizotinib [CAS 877399-52-5]

Crizotinib [CAS 877399-52-5]

Size

SKU:QM-0156490-01

£62.26 GBP
Sale Sold out
Shipping calculated at checkout.
Shipping calculated at checkout.
Quantity
View full details
  • Description

    Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition[1][2][3].

  • CAS Number

    [877399-52-5]

  • Molecular Formula

    C21H22Cl2FN5O

  • Molecular Weight

    450.34

  • Smiles

    ClC1=C(F)C=CC(Cl)=C1[C@H](OC2=CC(C3=CN(N=C3)C4CCNCC4)=CN=C2N)C

  • Target

    Anaplastic lymphoma kinase (ALK) ; c-Met/HGFR; Ligands for Target Protein for PROTAC; ROS Kinase

  • Purity

    99.97

  • Solubility

    DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H317, H319, H341, H400

  • Precautions

    H317, H319, H341, H400

Your cart
Variant Variant total Quantity Price Variant total
5 mgQM-0156490-01
5 mgQM-0156490-01
£62.26/ea
£0.00
£62.26/ea £0.00
10 mgQM-0156490-02
10 mgQM-0156490-02
£89.13/ea
£0.00
£89.13/ea £0.00
10 mM - 1 mLQM-0156490-03
10 mM - 1 mLQM-0156490-03
£95.88/ea
£0.00
£95.88/ea £0.00
50 mgQM-0156490-04
50 mgQM-0156490-04
£115.00/ea
£0.00
£115.00/ea £0.00
100 mgQM-0156490-05
100 mgQM-0156490-05
£188.51/ea
£0.00
£188.51/ea £0.00
200 mgQM-0156490-06
200 mgQM-0156490-06
£215.24/ea
£0.00
£215.24/ea £0.00
500 mgQM-0156490-07
500 mgQM-0156490-07
£312.44/ea
£0.00
£312.44/ea £0.00

View cart
0

Total items

£0.00

Product subtotal

Taxes, discounts and shipping calculated at checkout.
View cart

Crizotinib [CAS 877399-52-5]

Crizotinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.