Cyclosporin A [CAS 59865-13-3]
Cyclosporin A [CAS 59865-13-3]
SKU:QM-0158638-01
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Product Details
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Description
Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM[3]. Cyclosporin A also inhibits CD11a/CD18 adhesion[8].
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CAS Number
[59865-13-3]
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Molecular Formula
C62H111N11O12
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Molecular Weight
1202.61
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Smiles
C/C=C/C[C@H]([C@@H](O)[C@@]1(N(C)C([C@]([H])(C(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@]([H])(CC(C)C)N(C)C([C@@H](C)NC([C@H](C)NC([C@@H](N(C([C@@]([H])(NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)=O)=O)=O)=O)=O)[H])C
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Target
Antibiotic; Complement System; Cyclophilin; Molecular Glues
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Isoform
Cyclophilin D
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Purity
99.94
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Solubility
DMSO : 62.5 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H350, H360
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Precautions
H302, H350, H360
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Cyclosporin A [CAS 59865-13-3]
Cyclosporin A is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.