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Dacomitinib [CAS 1110813-31-4]

Dacomitinib [CAS 1110813-31-4]

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QM-0144135-01

£131.88 GBP
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Product Details

  • Description

    Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively[1].

  • CAS Number

    [1110813-31-4]

  • Molecular Formula

    C24H25ClFN5O2

  • Molecular Weight

    469.94

  • Smiles

    O=C(/C=C/CN1CCCCC1)NC2=CC3=C(C=C2OC)N=CN=C3NC4=CC=C(C(Cl)=C4)F

  • Target

    Apoptosis; EGFR

  • Isoform

    EGFR/ErbB1/HER1; ErbB2/HER2; ErbB4/HER4

  • Purity

    99.74

  • Solubility

    DMSO : 38.89 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0144135-01
5 mgQM-0144135-01
£131.88/ea		 £0.00
£131.88/ea £0.00
10 mM - 1 mLQM-0144135-02
10 mM - 1 mLQM-0144135-02
£142.00/ea		 £0.00
£142.00/ea £0.00
10 mgQM-0144135-03
10 mgQM-0144135-03
£248.04/ea		 £0.00
£248.04/ea £0.00
50 mgQM-0144135-04
50 mgQM-0144135-04
£414.50/ea		 £0.00
£414.50/ea £0.00
100 mgQM-0144135-05
100 mgQM-0144135-05
£614.98/ea		 £0.00
£614.98/ea £0.00
200 mgQM-0144135-06
200 mgQM-0144135-06
£796.01/ea		 £0.00
£796.01/ea £0.00
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Dacomitinib [CAS 1110813-31-4]

Dacomitinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.