Dasatinib [CAS 302962-49-8]

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SKU:QM-0081562-01

£57.09 GBP

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Product Details

Description
Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC50s of [1]. Dasatinib also induces apoptosis and autophagy.
CAS Number
[302962-49-8]
Molecular Formula
C22H26ClN7O2S
Molecular Weight
488.02
Smiles
O=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C
Target
Apoptosis; Autophagy; Bcr-Abl; Src
Isoform
Bcr-Abl
Concentration
10mM
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335
Precautions
H302, H315, H319, H335

Your cart
Variant	Variant total	Quantity	Price	Variant total
10 mgQM-0081562-01	10 mgQM-0081562-01 £57.09/ea	£0.00	Quantity	£57.09/ea	£0.00

50 mgQM-0081562-02	50 mgQM-0081562-02 £72.61/ea	£0.00	Quantity	£72.61/ea	£0.00

100 mgQM-0081562-03	100 mgQM-0081562-03 £101.50/ea	£0.00	Quantity	£101.50/ea	£0.00

10 mM - 1 mLQM-0081562-04	10 mM - 1 mLQM-0081562-04 £109.38/ea	£0.00	Quantity	£109.38/ea	£0.00

200 mgQM-0081562-05	200 mgQM-0081562-05 £116.13/ea	£0.00	Quantity	£116.13/ea	£0.00

500 mgQM-0081562-06	500 mgQM-0081562-06 £198.23/ea	£0.00	Quantity	£198.23/ea	£0.00

1 gQM-0081562-07	1 gQM-0081562-07 £272.35/ea	£0.00	Quantity	£272.35/ea	£0.00

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Dasatinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.