Decitabine [CAS 2353-33-5]

Size 100 mg 500 mg 1 g 2 g

SKU:QM-0157098-01

£78.82 GBP

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Product Details

Description
Decitabine (NSC 127716) is an orally active deoxycytidine analogue antimetabolite and a DNA methyltransferase inhibitor. Decitabine incorporates into DNA in place of cytosine can covalently trap DNA methyltransferase to DNA causing irreversible inhibition of the enzyme. Decitabine induces cell G2/M arrest and cell apoptosis. Decitabine has potent anticancer activity[1][2].
CAS Number
[2353-33-5]
Molecular Formula
C8H12N4O4
Molecular Weight
228.21
Smiles
O[C@H]1C[C@H](N2C(N=C(N)N=C2)=O)O[C@@H]1CO
Target
Apoptosis; DNA Methyltransferase; Nucleoside Antimetabolite/Analog
Isoform
DNMT1; DNMT3
Concentration
10mM
Purity
99.97
Solubility
DMSO : ≥ 50 mg/mL|H2O : 20 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, protect from light)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335, H341, H360
Precautions
H302, H315, H319, H335, H341, H360

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Variant	Variant total	Quantity	Price	Variant total
100 mgQM-0157098-01	100 mgQM-0157098-01 £78.82/ea	£0.00	Quantity	£78.82/ea	£0.00

500 mgQM-0157098-02	500 mgQM-0157098-02 £238.32/ea	£0.00	Quantity	£238.32/ea	£0.00

1 gQM-0157098-03	1 gQM-0157098-03 £363.47/ea	£0.00	Quantity	£363.47/ea	£0.00

2 gQM-0157098-04	2 gQM-0157098-04 £614.98/ea	£0.00	Quantity	£614.98/ea	£0.00

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Decitabine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.