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Docetaxel [CAS 114977-28-5]

Docetaxel [CAS 114977-28-5]

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SKU:QM-0157389-01

£108.25 GBP
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  • Description

    Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer activity[1][3].

  • CAS Number

    [114977-28-5]

  • Molecular Formula

    C43H53NO14

  • Molecular Weight

    807.88

  • Smiles

    O=C(OC(C)(C)C)N[C@@H](C1=CC=CC=C1)[C@H](C(O[C@@H]2C(C)=C([C@@H](O)C([C@@]3(C)[C@]([C@@](CO4)(OC(C)=O)[C@@]4([H])C[C@@H]3O)([H])[C@@H]5OC(C6=CC=CC=C6)=O)=O)C(C)(C)[C@@]5(O)C2)=O)O

  • Target

    Apoptosis; Endogenous Metabolite; Microtubule/Tubulin

  • Purity

    99.94

  • Solubility

    DMSO : 100 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H315, H319, H341, H360, H362, H372

  • Precautions

    H315, H319, H341, H360, H362, H372

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Variant Variant total Quantity Price Variant total
100 mgQM-0157389-01
100 mgQM-0157389-01
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10 mM - 1 mLQM-0157389-02
10 mM - 1 mLQM-0157389-02
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200 mgQM-0157389-03
200 mgQM-0157389-03
£143.13/ea
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1 gQM-0157389-04
1 gQM-0157389-04
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Docetaxel [CAS 114977-28-5]

Docetaxel is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.